Thursday, December 5, 2019

Physical Properties of Group 17 (halogens)





Physical properties of group 17 (halogens) (chapter 12 part 1)

The first 5 elements are called halogens

Group 17 has 7 valence electrons distributed between s and p orbitals where s orbital is completely filled and p orbital has 5 electrons

Group 17 acquires one electrons to reach electron configuration of nearest noble gas electron configuration

Going down the group the color of halogens gets darker 

Melting and boiling points both increase going down the group

Volatility decreases down the group due to the increase of atomic size, and van der Waals’ forces between molecules.

Visit us on:

https://www.youtube.com/channel/UCzXxV4xER9NIWt316gfeO1w

https://brightmindschemistry.blogspot.com

https://chemistrybrightminds.wordpress.com/

https://brighteningmind.wixsite.com/channel

https://www.facebook.com/BrightMinds

Tuesday, November 26, 2019

Group 2 Chemical Properties (Part 2 )


Group 2 chemical properties (chapter 11 -  part 2):
• Group 2 burns in presence of oxygen forming metal oxides
• Group 2 oxides dissolve in water giving alkaline solution
• We can use flame color test to identify group 2 elements
• Beryllium reacts with steam water at high temperature forming beryllium oxides and hydrogen
• Calcium readily reacts with water forming hydroxides and hydrogen
• Group 2 alkalinity of group 2 hydroxides increases down the group due to the increase in solubility
• Solubility of group 2 sulfates decreases down group 2
• All group 2 carbonates are insoluble in water except for Beryllium
• All group 2 reacts with dilute acid forming salt and water
• Except for formed magnesium sulfate salt, group 2 formed sulfates tend to form insoluble layer on carbonate preventing further reaction
• Dilute hydrolylic acid reaction with group 2 forming soluble chloride salts
• Carbonate and nitrate decompose given off metal oxide
• Temperature at which thermal decomposition takes place increases down group 2
Uses of group 2 compounds: Limestone (calcium carbonate):
1- There are many types of limestone that provide useful rocks for building
2- Marble is another form of calcium carbonate used as a building material such as tiles
3- Calcium carbonate also used to make cement:
First step is roasting limestone in lime kiln
At high temp. in the kiln calcium carbonate decomposes to calcium oxide (quicklime) that is roasted and mixed with clay to make cement
Cement can also be mixed with sand and small pieces of rock to make concreter
4- Slaked lime (calcium hydroxide Ca(OH)2):
Used to raise pH of acidic soil because calcium hydroxide is basic it reacts with acids in the soil and neutralize them raising the pH of the soil
5- Magnesium:
a. Soft light metal
b. Magnesium metal can be used an easily-burned substance with a bright light in photographic flash bulbs.
c. Epsom salts (magnesium sulfate):
d. Relieves pain and muscle cramp
6- Group 2 salts and fireworks:
• Barium - Barium is used to create green colors in fireworks and it can also help stabilize other volatile elements.
• Calcium - Calcium is used to deepen firework colors. Calcium salts produce orange fireworks.
• Magnesium - Magnesium burns a very bright white, so it is used to add white sparks or improve the overall brilliance of a firework.
• Strontium - Strontium salts impart a red color to fireworks. Strontium compounds are also important for stabilizing fireworks mixtures.
Visit us on:
https://www.youtube.com/channel/UCzXxV4xER9NIWt316gfeO1w
https://brightmindschemistry.blogspot.com
https://chemistrybrightminds.wordpress.com/
https://brighteningmind.wixsite.com/channel
https://www.facebook.com/BrightMinds

Saturday, November 23, 2019

The truth behind Collagen peptides

Collagen is the most abundant insoluble protein in animals, it is found in the extracellular space of connective tissue, it comprises three peptide chains that bundle together forming the distinct triple left-handed helix shape of collagen. 
The triple chain, Tropocollagen, is a supercoil with a diameter of 1.4nm and made up of 3 helices, each helix comprises around 1000 amino acid residues.
The three amino acids characteristic in the repeating units of collagen helix are glycine, proline, and hydroxyproline. The triple-helix motif is Gly-Y-X, where Y can either be proline or hydroxyproline, and X can be any other amino acid. Each collagen unit has 3.3 residues per turn and 0.54nm distance per pitch. The three-stranded helices are held together by the hydrogen bond between NH glycine hydrogen and C=O of the adjacent polypeptide. The angle of C-N peptidyl-proline or peptidyl-hydroxyproline is fixed, which makes the three peptide chains fold into a helix (Lodish H, 2000)

Cells and tissues in mammals are supported by collagen network; there are at least 16 types of collagen, about 80 to 90% of our body consists of three common types of collagen I, II and III collagen.

Type I collagen mostly found in bone (main component of the organic part of bone), dermis, tendon, ligaments and cornea. Type II collagen is found in cartilage, vitreous body, nucleus pulposus, and type III collagen found in tissues of the skin, vessel wall, reticular fibers of most tissues (lungs, liver, spleen, etc.) (Gelse, 2003).
Data in the figure obtained from (Buehler, 2006)

It is hard to study collagen metabolism; studies show that the triple-helical molecules are extracted by secretory vesicles from the Golgi compartment into the extracellular space. The triple helix is cleaved by proteases (N and C) according to the type of the produced collagen, both proteases (N and C), are Zn dependent. The process of cleavage requires the presence of copper and vitamin C as well, yet all data suggests that it is hard to study collagen metabolism because it turns over slowly (Gelse, 2003).

Aging decreases the amount of collagen that reaches the extracellular space, In addition the degradation of tropocollagen by extracellular proteases leaves behind N- and C- terminal fragments that accelerate the breaking down of collagen by metalloproteinases matrix (MMPs) (Rennie, 1999).

But can the oral intake of collagen peptide restore body collagen?
Exploring the extent of collagen consumption is essential to comprehend the possibilities of collagen to reach the extracellular space when orally consumed.
The main questions would be; does the collagen peptide consumed orally reaches skin and bone? Does the digestion process affect the integrity of the collagen peptide?
Skin collagen degrades by metalloproteinases matrix (MMPs), topically administration of collagen peptide (CH) delays aging, and treats the skin. The benefit of ingestion collagen peptide remains obscure, the clinical community agreed on the fact that ingestion of collagen in its hydrolyzed form suppresses the MMP2 activities leading to a reduction of wrinkles (Zague, 2011), still extensive studies were needed to establish concrete results.
Studies that investigated the integrity of the ingestion of peptide showed that collagen hydrolysate can cross the intestinal barrier reaching blood circulation, and becomes available for the metabolic process, and storage in the skin. In fact, the ingestion of a rich collagen diet promotes skin elasticity, reduces pain for people suffering from osteoarthritis, inhabit cardiovascular damage and collagen driven from fish has potent anti-oxidative effect. Collagen hydrolysate supplements proved to relieve joints pain due to heavy exercises in athletes. (Clark, 2008).
A double-blind placebo-controlled trial conducted on 69 women, aged between 35 and 55, for 8 weeks, showed that the oral intake of collagen hydrolysate enhances the skin elasticity, and acts as a skin moisturizer in the elderly women (Proksch, 2014).
An interesting study on rats showed that oral intake of collagen peptide in the presence and absence of calcium diet, both increase the bone mass in rats. The rates with high collagen intake exhibited hypertrophy in kidneys, without undesirable effects. The study provides another evidence on the benefit of collagen oral intake on reducing osteopenia that occurs with aging. (Wu, 2004)


Why there are still some concerns?

In the manufacture of collagen, the heavy metal test allows levels not to exceed the approved human consumption. The effect of long collagen consumption is not completely investigated; the accumulation of heavy metals and contaminant effect would be seen after a long time, where most studies were performed for short periods.

Many other potential sources have been investigated, in Gómez-Guillén review (Gómez-Guillén, 2011). The review is considered to be a useful source for information on alternative sources.

A clear picture of the effect of collagen intake can be driven from the Japanese diet, the Japanese diet contains a large portion of collagen. But where collagen-rich diet is absent, collagen supplements are a very useful source of collagen. 
Till now collagen peptide supplement proved to be of a great benefit as long as the quality of the product is been monitored. 

References

Buehler, M. (2006). Nature designs tough collagen: explaining the nanostructure of collagen fibrils. Proceedings of the National Academy of Sciences, 103(33), 12285-12290.
Clark, K. S. (2008). 24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain. Current medical research and opinion, 25(5), 1485-1496.
Gelse, K. P. (2003). Collagens—structure, function, and biosynthesis. Advanced drug delivery, 55(12), 1531-1546.
Gómez-Guillén, M. G.-C. (2011). Functional and bioactive properties of collagen and gelatin from alternative sources: A review. Food hydrocolloids, 25(8), 1813-1827.
Lodish H, B. A. (2000). Collagen: The Fibrous Proteins of the Matrix. In B. A. Lodish H, Molecular Cell Biology. 4th edition. New York: W. H. Freeman. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK21582/
Proksch, E. S. (2014). Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis. Skin pharmacology and physiology, 27(3), 113-119.
Rennie, M. J. (1999). Teasing out the truth about collagen. The Journal of physiology, 521.
Wu, J. F. (2004). Assessment of effectiveness of oral administration of collagen peptide on bone metabolism in growing and mature rats. Journal of bone and mineral metabolism, 22(6), 547-553.
Zague, V. d.-S. (2011). Collagen hydrolysate intake increases skin collagen expression and suppresses matrix metalloproteinase 2 activity. Journal of medicinal food, 14(6), 618-624.









Friday, November 15, 2019

Group 2 physical properties part 1



Group 2 (alkaline earth metals) physical properties (Chapter 11-Part 2):
The reason behind naming group 2 alkaline earth metals is that they form alkaline solution when dissolve in water.
Metallic radius is half the distance between the nuclei in a giant metallic lattice.
Metallic radius increases down group 2 because the atomic number increases and extra level is added down the group
Group 2 have high electric conductivity and the thermal conductivity.
Group 2 melting point trend:
Melting points decrease down the group although some irregularities are seen.
The reason behind the low melting point of magnesium comparing to calcium is the arrangement of metallic lattice for both elements.
• Be 1544, 1560, 1018, hcp (face centered cubic) at RT
• Mg 922, 755, 705, hcp (hexagonal close packed) at RT
• Ca 940, 1114, 1063, fcc at RT
• Sr 900, 1050, 1030, fcc at RT
• Ba 635, 1000, 709, bcc (body center cubic) at RT
Calcium has fcc arrangement where magnesium has hcp crystal packing, the high ductility makes melting point of calcium higher than magnesium.
Density trend for group 2 elements:
Density increases down group 2 as atomic number increases.
Again, some irregularities in density are also seen, calcium has lower density than magnesium. Crystal lattice of calcium has 14 atoms where magnesium has 19 atoms in its lattice which makes density of calcium lower than magnisium.
Visit us on:
https://www.youtube.com/channel/UCzXxV4xER9NIWt316gfeO1w
https://brightmindschemistry.blogspot.com
https://chemistrybrightminds.wordpress.com/
https://brighteningmind.wixsite.com/channel
https://www.facebook.com/BrightMinds

Saturday, November 9, 2019

Why the sky is blue and the clouds are white?



Ever wondered why the sky is blue?
The sun is a large shiny star that sends light to all surrounding space.
Light can travel in a vacuum, and it travels to earth.
So, if the sun is sending white light, why the sky appear blue!
The light is an electromagnetic spectrum, electromagnetic wave, each wave travels from the sun with a different wavelength and different frequency.
The light coming from the sun contains all types of electromagnetic spectrum, such as; microwaves, infrared light, ultraviolet light, X-rays, gamma-rays, and visible light.
White light is a mixture of wavelengths, of the visible portion, of the electromagnetic spectrum (visible spectrum).
We see all the rainbow colors mixed as white light, but if we passed light through a prism, we will see rainbow colors.
Each color we see comprise a certain amount of energy, has a certain wavelength, and definite frequency.
When white light falls on your red T-shirt, your T-shirt absorbs all colors except for red. Your T-shirt reflects the red color, and you see your T-shirt in red.
A similar thing happens in the sky. When the white color coming from the sun interact with the atmosphere, the air particles absorb all visible colors except for blue.
Air particles scatter the blue color in all directions, this is why we see the sky in blue, and we see the scattered blue color.
But why the clouds appear white?
Clouds are made of water vapor, water vapor consists of large water molecules that scatter all colors.
We see these colors mixed as a white color, and the clouds appear white. Water molecules are transparent, but they are so large that they scatter all visible spectrum and appear white.
So why clouds sometimes appear gray?
The scattered light from the white clouds scatter in all directions, but on a rainy day, the water molecules at the bottom of the cloud become so dense to allow the light to pass, where the top part of the cloud scatter light. The clouds become dark from the bottom, and light from the top, and we see them in gray.
Visit us on:
https://www.youtube.com/channel/UCzXxV4xER9NIWt316gfeO1w
https://brightmindschemistry.blogspot.com
https://chemistrybrightminds.wordpress.com/
https://brighteningmind.wixsite.com/channel
https://www.facebook.com/BrightMinds

Tuesday, November 5, 2019

Period 3 oxides and chlorides (Periodicity of chemical properties - Part 4)




Periodicity of chemical properties (Chapter 10 - Part 4):
Going across a period the elements get more electronegative as electrons are more strongly attracted by the increasing positive nuclear charge.
2- The electronegativity and acidic/basic nature of the Period 3 oxides:
a.  Na, Mg, and Al form an ionic bond with oxygen in their oxides forming a large lattice.
b. Silicon bond covalently with oxygen to form SiO2 that has large molecular lattice.
3- The high melting points of ionic oxides make them suitable to be used in:
a. magnesium oxide to line the inside of furnaces.
b.  aluminum oxide and silicon dioxide are used to make ceramics, with giant covalent structures designed to withstand high temperatures and provide electrical insulation.
c. P, S and chlorine bond covalently with oxygen forming small molecules.
 4- Chlorides of Period 3 elements:
Chlorine has electronegativity equal to -1 where the rest of period three elements form positive ions with chlorine because of lower electronegativity comparing to chlorine.
a. The first three elements chlorides dissolve in water forming hydrate ions.
b. AlCl3 dimerize into Al2Cl6 solid hydrate that breaks down releasing hydrogen ions that react with chlorine atoms forming white fumes.
c. Sulfur and phosphorus both form chlorides that hydrolyze forming hydrogen chloride fumes.
Visit us on:
https://brightmindschemistry.blogspot.com
https://chemistrybrightminds.wordpress.com/
https://brighteningmind.wixsite.com/channel
https://www.facebook.com/BrightMinds

Saturday, November 2, 2019

Period 3 chemical properties (part 3)



Chemical properties periodicity in periodic table ( CH10  part 3)
Period 3 chemical properties
Reaction of period 3 elements with chlorine gas
Reaction of period 3 elements with water
Reaction of period 3 elements with oxygen
period 3 oxides
Visit us on:
https://brightmindschemistry.blogspot.com
https://chemistrybrightminds.wordpress.com/
https://brighteningmind.wixsite.com/channel
https://www.facebook.com/BrightMinds

Wednesday, October 30, 2019

Physical properties periodicity in periodic table (Part2)



Physical properties periodicity in periodic table (CH10 Part2)
Periodic patterns of melting points and electrical conductivity
Periodic patterns of first ionization energies
Why silicon has highest melting point in period no. 3?
Why aluminum has first ionization energy lower than magnesium?
Why phosphorous has higher first ionization energy higher than sulfur?
Visit us on:
https://brightmindschemistry.blogspot.com
https://chemistrybrightminds.wordpress.com/
https://brighteningmind.wixsite.com/channel
https://www.facebook.com/BrightMinds




Monday, October 28, 2019

Physical properties periodicity in periodic table ( Part 1)



Physical properties periodicity in periodic table CH10 Part1
Atomic radius decreases a cross period and increases down the group
Ionic radius reduces for metals across period but increases for non-metals a cross period
Visit us on:
https://brightmindschemistry.blogspot.com
https://chemistrybrightminds.wordpress.com/
https://brighteningmind.wixsite.com/channel
https://www.facebook.com/BrightMinds

Global Warming: Is Summer Getting Hotter?




        In the past few years, the average temperature increased to a noticeable level. Summer season became hotter and hotter. Many plants that used to grow in cold weather started to retreat to polar zones. Although the increase in the temperature may not appear much, the effect on the ecosystem is dramatic (Root).

Increasing temperature results in a decrease in plant biodiversity


          The short periods of ice during winter season near mountains areas affect the biodiversity of the plants in colder zones. The thickness of the glacier layers showed a decrease in the thickness during the past hundred years and the extent of summer seasons near the Arctic zone. The increase in the temperature forced the alpine floras to the top of the mountains. The cold zone floras bloom extended due to extend of summer. Although the extent in the blooming periods of the floras during the summer season; the continuous increase in the temperatures in colder zones resulted in a crawl of warm zone floras cover in the Arctic and a retreat of cold zones flora cover. The retreat of colder flora against the warm flora cover threatens the biodiversity near the mountain’s areas; where the cold climate is overcome by a longer summer season (Crawford).

Evidence of increasing temperature affects plant growth and yield


           A team of researchers in the International Rice Research Institute explored the effect of increasing temperature and global warming on the yield of rice. The group examined the yield of the institute farm between the years 1992 and 2003. They correlated the 10% decline of the rice grain yield with the increase in the annual temperature minimum and maximum, 0.35oC and 1.3oC respectively. The group concluded that the decline was in close relation to the increase in the temperature during night time between the investigated years (Peng).

The increase in carbon dioxide ratios


          The emission of carbon dioxide gas into the atmosphere coming from burning fuel due to industrialization increased the level of carbon dioxide gas level. The increase in levels of greenhouse gas—carbon dioxide gas— showed a strong relation to the increase of the temperature (Bazzaz). Carbon dioxide gas (CO2) in the atmosphere acts as a trap for the sun rays, preventing rays from reflecting into space. As the level of CO2 increases, an increase in the rate of aquatic phytoplankton and algae photosynthesis happens leading to blooming effect. Many studies argued that although the increase of photosynthesis rates should be accompanied by a high release of oxygen gas (O­2), the decomposition of a large scale of phytoplankton results in the consumption of O2 in the lower part of the water body. Recently, many lakes in Europe suffer the Eutrophication—well-nourished— that cause less biodiversity in lakes and threaten the aquatic animal’s life (Smith).

           Many other factors are investigated to give a complete picture of factors accompanying global warming. Researchers are working hard to contain the problems associated with global warming.
The global warming started to increase to an alarming level that cannot be ignored. People should stop acting as if the researchers’ results are speculations and start treating global warming as a fact already happening.




References:



Bazzaz, F.A. "The response of natural ecosystems to the rising global CO2 levels ." Annual review of ecology and systematics 21.1 (1990): 167-196.

Crawford, R.M. "Cold climate plants in a warmer world." Plant Ecology & Diversity 1.2 (2008): 285-297.

Peng, S., Huang, J., Sheehy, J.E., Laza, R.C., Visperas, R.M., Zhong, X., Centeno, G.S., Khush, G.S. and Cassman, K.G. "Rice yields decline with higher night temperature from global warming." Proceedings of the National Academy of Sciences 101.27 (2004): 9971-9975.

Root, T. L., Price, J. T., Hall, K. R., Schneider, S. H., Rosenzweig, C., & Pounds, J. A. "Fingerprints of global warming on wild animals and plant." Nature 421.6918 (2003): 57-60.

Smith, V.H., Tilman, G.D. and Nekola, J.C. "Eutrophication: impacts of excess nutrient inputs on freshwater, marine, and terrestrial ecosystems." Environmental pollution 100.1-3 (1999): 179-196.

Saturday, October 19, 2019

Rates of reaction & Factors affect rate of reaction (part 2)


Rate of reaction
Effect of  temperature and catalyst on rate of reaction
Type of catalysts
Biological catalysts: Enzymes
Visit us on:
https://brightmindschemistry.blogspot.com
https://chemistrybrightminds.wordpress.com/
https://brighteningmind.wixsite.com/channel
https://www.facebook.com/BrightMinds

Wednesday, October 16, 2019

Rates of reaction & Factors affect rate of reaction (part 1)



Reaction Kinetics
Collision theory
Activation energy
The effect of concentration on rate of reaction
Visit us on:
https://brightmindschemistry.blogspot.com
https://chemistrybrightminds.wordpress.com/
https://brighteningmind.wixsite.com/channel
https://www.facebook.com/BrightMinds

Friday, October 11, 2019

Chemistry Bright Minds _2





Subscribe and start learning Chemistry
https://www.youtube.com/channel/UCzXxV4xER9NIWt316gfeO1w
Visit us on:
https://brightmindschemistry.blogspot.com
https://chemistrybrightminds.wordpress.com/
https://brighteningmind.wixsite.com/channel
https://www.facebook.com/BrightMinds

Thursday, October 10, 2019

Equilibria in gas reactions



Equilibria in gas reactions: the equilibrium constant Kp  (Chapter  8 part 3)
Equilibrium expressions involving partial pressures Haber process in synthesis of ammonia and reaction equilibria synthesis of sulfuric acid and reaction equilibria  


Sunday, October 6, 2019

Difference between absorption and emission spectra



White light produces a continuous spectrum when passes through a prism.
 If a cold gas tube placed in front of the source of the photons the gas atoms absorb energy to move electrons to an excited state and the produced is the absorption spectrum.
 When the gas cools down electrons return to ground state and atom emits or release the emission spectrum or energy they gained before.
 Each element has its specific fingerprint line-spectrum.

Subscribe and start learning Chemistry
https://www.youtube.com/channel/UCzXxV4xER9NIWt316gfeO1w
Visit us on:
https://brightmindschemistry.blogspot.com
www.facebook.com/ChemistryBrightMinds
https://chemistrybrightminds.wordpress.com/
https://brighteningmind.wixsite.com/channel

Tuesday, October 1, 2019

How to calculate the atomic radius? Trend of atomic radius in periodic table



Atomic radius is half the distance between two nuclei (r=d/2)
The atomic radius decreases across a period from left to right
The atomic radius increases down a group due to the increase in the number of levels
Visit us on:
https://brightmindschemistry.blogspot.com
Facebook@brightmindschannel
https://chemistrybrightminds.wordpress.com/
https://brighteningmind.wixsite.com/channel

Saturday, September 28, 2019

Reversible reactions and reaction equilibrium



Reversible reactions and equilibrium
Le Chatelier’s principle
Characteristic of equilibrium
Factors affect position of equilibrium: Temperature, Concentration and pressure
Exercises on the factors that can shift position of equilibrium
Catalysts have no effect on position of equilibrium

Subscribe for more videos:
https://www.youtube.com/channel/UCzXxV4xER9NIWt316gfeO1w

Friday, September 27, 2019

Hydrogels as Wound Dressing


Hydrogels played a primary role in medicine in the last few decades because of their outstanding properties. Hydrogels have a unique three-dimension structure that enables them to hold water or any biological fluids for a long time. The crosslink (tie-points, junctions) of the three-dimension structure allows them to be insoluble in water, while their ability to hold biological fluids enables them to mimic the human tissue (Khule, 2018).



Many researchers have used hydrogels unique properties and tuned them to be used in pharmaceutical applications. Temperature, pH, ionic strength, and salts are parameters used as physiological stimuli to control the hydrogels (Kamoun, 2017).

The three forms of hydrogels are; hydro gel’s form where the gel is hydrated by water or fluids. In contrast, removing the water from the gel “xerogel” cause the structure to collapse, and to lose its functionality. The third important form is called Aerogels, it is a hydrogel where water or liquid was removed using freeze-drying or organic solvents, without disturbing the gel mesh, and the left aerogels are very light and highly porous  (Vowden, 207).

Hydrogels used as a wound dressings showed satisfactory results in wound healing. They do not stick to the wound and easily replaced without damaging the formed epidermis. Gels nature make them smooth pain and cool the skin, which relief the patient. The tight mesh size prevents wound infection, and maintain permeability required for a drug to penetrate. The advantage that makes hydrogels perfect candidate in wound healing is the dressings are transparent, which help in monitoring the wound (Vowden, 207). They proved excellent ability in treating moderately exudating wounds and minor burns. There are many products in the market can be used as a dressing or topical cream such as Restore- hydrogel.


References


Kamoun, E. A. (2017). A review on polymeric hydrogel membranes for wound dressing applications: PVA-based hydrogel dressings. Journal of advanced research, 217-233.
Khule, A. B. (2018). As a review on hydrogel, pharmaceutical sciences.
Vowden, K. &. (207). Wound dressings: principles and practice. Surgery (Oxford), 489-494.